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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cas5eCRISPR-associated protein Cas5; Derived by automated computational analysis using gene prediction method: Protein Homology. (241 aa)    
Predicted Functional Partners:
ORV18301.1
CRISPR-associated protein Cas3; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.990
cas2e
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.965
cas1
Type I-E CRISPR-associated endonuclease Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
   
 0.961
casA
Type I-E CRISPR-associated protein Cse1/CasA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.956
casB
Type I-E CRISPR-associated protein Cse2/CasB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.956
cas7e
Type I-E CRISPR-associated protein Cas7/Cse4/CasC; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.956
cas6e
Type I-E CRISPR-associated protein Cas6/Cse3/CasE; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.956
ORV18165.1
Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.420
Your Current Organism:
Mycobacterium celatum
NCBI taxonomy Id: 28045
Other names: ATCC 51131, CCUG 39185, CDC 90-0899, CIP 106109, DSM 44243, JCM 12373, M. celatum, NCTC 13729
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