close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ORV18178.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (363 aa)    
Predicted Functional Partners:
ORV18179.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
     0.967
ORV18180.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
     0.967
ORV18176.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.949
ORV18174.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
     0.926
ORV18175.1
AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.862
ORV18177.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.862
rskA
Anti-sigma factor; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK. ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, Rip1), while cytoplasmic proteases finish degrading the regula [...]
  
     0.676
ORV18380.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.672
ORV09625.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.655
ORV19155.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.621
Your Current Organism:
Mycobacterium celatum
NCBI taxonomy Id: 28045
Other names: ATCC 51131, CCUG 39185, CDC 90-0899, CIP 106109, DSM 44243, JCM 12373, M. celatum, NCTC 13729
Server load: medium (54%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.