Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
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[Homology]
Score
ORV08317.1Glutamate--cysteine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (492 aa)    
Predicted Functional Partners:
egtB
iron(II)-dependent oxidoreductase EgtB; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family.
  
 
 0.868
ORV07006.1
Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.840
ORV19033.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.580
ORV14910.1
Sulfatase-modifying factor 1; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.573
ORV13625.1
Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.560
ORV08316.1
Antitoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.555
vapC-24
Ribonuclease; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.
       0.554
ORV14084.1
GNAT family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.526
ddl
D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
    
  0.470
ORV09901.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.457
Your Current Organism:
Mycobacterium celatum
NCBI taxonomy Id: 28045
Other names: ATCC 51131, CCUG 39185, CDC 90-0899, CIP 106109, DSM 44243, JCM 12373, M. celatum, NCTC 13729
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