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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobB-3NAD-dependent deacylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sirtuin family. Class III subfamily. (237 aa)    
Predicted Functional Partners:
ORV18009.1
ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.878
nadE
NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.848
nadD
Nicotinate-nicotinamide nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
   
 0.824
ORV14806.1
Mycofactocin system transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.814
ORV11035.1
Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.802
ORV18536.1
Nicotinamidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.796
ORV18007.1
NADH pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.795
ppnK
NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
 
 0.795
ORV18026.1
TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.794
ORV07859.1
Pyridine nucleotide-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.793
Your Current Organism:
Mycobacterium celatum
NCBI taxonomy Id: 28045
Other names: ATCC 51131, CCUG 39185, CDC 90-0899, CIP 106109, DSM 44243, JCM 12373, M. celatum, NCTC 13729
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