Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
uppPhosphomannomutase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (207 aa)    
Predicted Functional Partners:
pyrH
UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
 
 0.955
pyrF
Orotidine 5'-phosphate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the OMP decarboxylase family. Type 2 subfamily.
  
 
 0.945
ORV34498.1
Pyrimidine-nucleoside phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.902
ORV27065.1
Cytosine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.890
pyrR
Uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
     
 0.824
surE
Hypothetical protein; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.822
ORV34452.1
Septum formation inhibitor Maf; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
     
  0.804
ORV20717.1
HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HAD-like hydrolase superfamily.
     
  0.804
upp-2
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
     
  0.804
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
    
 0.791
Your Current Organism:
Mycolicibacterium confluentis
NCBI taxonomy Id: 28047
Other names: ATCC 49920, CIP 105510, DSM 44017, JCM 13671, M. confluentis, Mycobacterium confluentis
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