node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ORV20626.1 | ORV22914.1 | AWB99_06590 | AWB99_25545 | Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.670 |
ORV20626.1 | ORV28433.1 | AWB99_06590 | AWB99_17855 | Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | 0.600 |
ORV20626.1 | ORV30812.1 | AWB99_06590 | AWB99_12800 | Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.667 |
ORV20626.1 | thyA | AWB99_06590 | AWB99_18685 | Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.884 |
ORV22914.1 | ORV20626.1 | AWB99_25545 | AWB99_06590 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.670 |
ORV22914.1 | ORV28433.1 | AWB99_25545 | AWB99_17855 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | 0.930 |
ORV22914.1 | ORV29712.1 | AWB99_25545 | AWB99_16155 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.670 |
ORV22914.1 | ORV30812.1 | AWB99_25545 | AWB99_12800 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.670 |
ORV22914.1 | ORV30823.1 | AWB99_25545 | AWB99_12805 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.482 |
ORV22914.1 | ORV32064.1 | AWB99_25545 | AWB99_10390 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.670 |
ORV22914.1 | thyA | AWB99_25545 | AWB99_18685 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.679 |
ORV28433.1 | ORV20626.1 | AWB99_17855 | AWB99_06590 | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.600 |
ORV28433.1 | ORV22914.1 | AWB99_17855 | AWB99_25545 | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.930 |
ORV28433.1 | ORV29712.1 | AWB99_17855 | AWB99_16155 | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.600 |
ORV28433.1 | ORV30812.1 | AWB99_17855 | AWB99_12800 | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.600 |
ORV28433.1 | ORV32064.1 | AWB99_17855 | AWB99_10390 | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.600 |
ORV28433.1 | thyA | AWB99_17855 | AWB99_18685 | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.891 |
ORV29712.1 | ORV22914.1 | AWB99_16155 | AWB99_25545 | Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.670 |
ORV29712.1 | ORV28433.1 | AWB99_16155 | AWB99_17855 | Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | 0.600 |
ORV29712.1 | ORV30812.1 | AWB99_16155 | AWB99_12800 | Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.732 |