STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ORV23249.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)    
Predicted Functional Partners:
recB
Exodeoxyribonuclease V subunit beta; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and rep [...]
     
 0.628
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
  
 
  0.604
ORV27019.1
3-oxoacyl-ACP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.562
ORV23090.1
FmdB family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.540
ORV20613.1
Beta-glucosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.533
ORV23829.1
Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
  
  
 0.502
rbfA
Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.
  
  
 0.447
secY
Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
   
 
 0.443
ORV23091.1
Flagellar biosynthesis protein FlgA; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.423
ORV34564.1
Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.419
Your Current Organism:
Mycolicibacterium confluentis
NCBI taxonomy Id: 28047
Other names: ATCC 49920, CIP 105510, DSM 44017, JCM 13671, M. confluentis, Mycobacterium confluentis
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