node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cbiC | cobB_1 | ERS852451_00875 | ERS852451_00882 | Cobalt-precorrin-8X methylmutase. | Cobyrinic acid A%2CC-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobT family. | 0.998 |
cbiC | cobD | ERS852451_00875 | ERS852451_00888 | Cobalt-precorrin-8X methylmutase. | Threonine-phosphate decarboxylase. | 0.940 |
cbiC | cobD-2 | ERS852451_00875 | ERS852451_00887 | Cobalt-precorrin-8X methylmutase. | Cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.965 |
cbiC | cobQ | ERS852451_00875 | ERS852451_00889 | Cobalt-precorrin-8X methylmutase. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.999 |
cbiC | cobS | ERS852451_00875 | ERS852451_00884 | Cobalt-precorrin-8X methylmutase. | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.923 |
cobB_1 | cbiC | ERS852451_00882 | ERS852451_00875 | Cobyrinic acid A%2CC-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobT family. | Cobalt-precorrin-8X methylmutase. | 0.998 |
cobB_1 | cobD | ERS852451_00882 | ERS852451_00888 | Cobyrinic acid A%2CC-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobT family. | Threonine-phosphate decarboxylase. | 0.983 |
cobB_1 | cobD-2 | ERS852451_00882 | ERS852451_00887 | Cobyrinic acid A%2CC-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobT family. | Cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.965 |
cobB_1 | cobQ | ERS852451_00882 | ERS852451_00889 | Cobyrinic acid A%2CC-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobT family. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.976 |
cobB_1 | cobS | ERS852451_00882 | ERS852451_00884 | Cobyrinic acid A%2CC-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobT family. | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.982 |
cobD | cbiC | ERS852451_00888 | ERS852451_00875 | Threonine-phosphate decarboxylase. | Cobalt-precorrin-8X methylmutase. | 0.940 |
cobD | cobB_1 | ERS852451_00888 | ERS852451_00882 | Threonine-phosphate decarboxylase. | Cobyrinic acid A%2CC-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobT family. | 0.983 |
cobD | cobD-2 | ERS852451_00888 | ERS852451_00887 | Threonine-phosphate decarboxylase. | Cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.994 |
cobD | cobQ | ERS852451_00888 | ERS852451_00889 | Threonine-phosphate decarboxylase. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.992 |
cobD | cobS | ERS852451_00888 | ERS852451_00884 | Threonine-phosphate decarboxylase. | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.921 |
cobD | gmhB | ERS852451_00888 | ERS852451_00552 | Threonine-phosphate decarboxylase. | D%2CD-heptose 1%2C7-bisphosphate phosphatase. | 0.940 |
cobD | hisB | ERS852451_00888 | ERS852451_01085 | Threonine-phosphate decarboxylase. | Imidazoleglycerol-phosphate dehydratase. | 0.982 |
cobD | hisD | ERS852451_00888 | ERS852451_01086 | Threonine-phosphate decarboxylase. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.952 |
cobD | hisH1 | ERS852451_00888 | ERS852451_01234 | Threonine-phosphate decarboxylase. | Imidazole glycerol phosphate synthase subunit HisH 1; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.911 |
cobD | pheA | ERS852451_00888 | ERS852451_01487 | Threonine-phosphate decarboxylase. | P-protein. | 0.924 |