STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CYME_CMO270CPlant organellar DNA polymerase. (948 aa)    
Predicted Functional Partners:
CYME_CML313C
Similar to ATP-dependent RNA helicase.
   
 
 0.991
CYME_CMT462C
Bacterial DNA polymerase I.
  
  
 
0.909
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
  
 
 0.683
CYME_CMP170C
Similar to formamidopyrimidine-DNA glycosylase.
  
  
 0.664
CYME_CMB035C
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
   
 0.662
CYME_CMN306C
Uncharacterized protein.
   
 0.635
CYME_CME067C
Exonuclease I.
  
 
 0.627
CYME_CMQ187C
DNA repair protein RAD50.
  
 
 0.599
CYME_CMS061C
Probable peptide methionine sulfoxide reductase.
   
  
 0.597
CYME_CMG079C
Similar to DNA excision repair protein ERCC-1.
     
 0.479
Your Current Organism:
Cyanidioschyzon merolae
NCBI taxonomy Id: 280699
Other names: C. merolae strain 10D, Cyanidioschyzon merolae strain 10D
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.