STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CYME_CML193CFatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (271 aa)    
Predicted Functional Partners:
CYME_CMC055C
Probable lathosterol oxidase; Belongs to the sterol desaturase family.
   
 
 0.928
CYME_CMJ009C
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
   
 
 0.794
CYME_CMS319C
Cytochrome P450, family 51; Belongs to the cytochrome P450 family.
   
 
 0.758
CYME_CMR093C
Cytochrome P450; Belongs to the cytochrome P450 family.
   
 
 0.758
CYME_CMH256C
Squalene monooxygenase.
   
 
 0.733
CYME_CMS109C
Similar to geranylgeranyl hydrogenase.
   
 
 0.733
CYME_CMM189C
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
   
 
 0.658
CYME_CMG178C
Squalene synthase.
  
 
 0.615
CYME_CMM166C
Phytoene synthase.
  
 
 0.615
CYME_CMO346C
Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...]
   
 
 0.607
Your Current Organism:
Cyanidioschyzon merolae
NCBI taxonomy Id: 280699
Other names: C. merolae strain 10D, Cyanidioschyzon merolae strain 10D
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