STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CYME_CMT273CType II DNA topoisomerase VI subunit B. (705 aa)    
Predicted Functional Partners:
CYME_CMQ111C
DNA topoisomerase VI subunit A.
 
 
 0.829
CYME_CML010C
Similar to DNA topoisomerase VI subunit A.
  
 
 0.665
CYME_CME071C
Similar to DNA topoisomerase VI subunit A.
  
 
 0.665
CYME_CMR274C
Similar to DNA topoisomerase VI subunit A.
  
 
 0.665
CYME_CMQ286C
DNA primase, bacterial-type.
      
 0.507
CYME_CMK284C
DNA primase, large subunit.
      
 0.507
CYME_CMS112C
Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
   
  
 0.507
CYME_CMO313C
DNA primase; Belongs to the eukaryotic-type primase small subunit family.
      
 0.507
CYME_CMH198C
Box H/ACA snoRNP component Nop10p.
      
 0.505
CYME_CMN210C
Eukaryotic translation initiation factor eIF-2 alpha subunit.
   
 
 0.490
Your Current Organism:
Cyanidioschyzon merolae
NCBI taxonomy Id: 280699
Other names: C. merolae strain 10D, Cyanidioschyzon merolae strain 10D
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.