STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
acsAacetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (656 aa)    
Predicted Functional Partners:
AFY49502.1
PFAM: Citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; Belongs to the citrate synthase family.
  
 0.985
AFY47702.1
Pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin.
  
 
 0.975
AFY48163.1
Pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin.
  
 
 0.975
AFY48933.1
Alcohol dehydrogenase, class IV; PFAM: Aldehyde dehydrogenase family; Iron-containing alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 0.964
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
   
 
 0.942
AFY47474.1
PFAM: Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family.
   
 0.939
AFY47203.1
PFAM: Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family.
   
 0.937
AFY49443.1
acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 0.933
accD
acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
    
 0.929
AFY46471.1
PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 binding domain; Biotin-requiring enzyme; TIGRFAM: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form.
  
 
 0.928
Your Current Organism:
Nostoc sp. PCC7524
NCBI taxonomy Id: 28072
Other names: N. sp. PCC 7524, NOSTOC SP. (STRAIN PCC 7524), Nostoc ATCC 29411, Nostoc ATCC29411, Nostoc PCC 7524, Nostoc PCC7524, Nostoc sp. (ATCC 29411), Nostoc sp. (PCC 7524), Nostoc sp. ATCC 29411, Nostoc sp. ATCC29411, Nostoc sp. PCC 7524
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