Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Lbir_0100Type II/III secretion system protein. (253 aa)    
Predicted Functional Partners:
Lbir_0591
General secretion pathway protein C.
  
 
 0.862
pilZ_2
Type IV pilus assembly PilZ.
  
     0.770
iraA
Small-molecule methyltransferase IraA.
  
     0.764
Lbir_2409
Hypothetical protein.
  
     0.762
Lbir_0101
Putative phosphate transport regulator.
       0.761
pitA_1
Phosphate transporter.
       0.759
damX
DamX-related protein.
 
     0.758
fliH
Polar flagellar assembly protein FliH.
 
  
 0.754
Lbir_2649
Hypothetical protein.
  
     0.746
xynY
Putative secreted esterase.
  
     0.733
Your Current Organism:
Legionella birminghamensis
NCBI taxonomy Id: 28083
Other names: ATCC 43702, CCUG 31233, CCUG 31233 A, CIP 103871, DSM 19232, JCM 7559, L. birminghamensis, NCTC 12437
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