Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mhpC_22-hydroxy-6-oxononadienedioate/2-hydroxy-6- oxononatrienedioate hydrolase. (268 aa)    
Predicted Functional Partners:
Lbir_0961
Histone methylation protein DOT1.
       0.772
Lbir_0960
Hypothetical protein.
       0.722
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
  0.626
Lbir_0950
Hypothetical protein.
       0.499
treS
Trehalose synthase/amylase TreS.
   
    0.443
hipB
Integration host factor subunit beta; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.
       0.418
cph2_5
Sensory box protein (GGDEF domain/EAL domain).
  
 
  0.406
Your Current Organism:
Legionella birminghamensis
NCBI taxonomy Id: 28083
Other names: ATCC 43702, CCUG 31233, CCUG 31233 A, CIP 103871, DSM 19232, JCM 7559, L. birminghamensis, NCTC 12437
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.