Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
acnAAconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (891 aa)    
Predicted Functional Partners:
prpC
2-methylcitrate synthase; Belongs to the citrate synthase family.
 
 0.997
gltA
Citrate synthase; Belongs to the citrate synthase family.
 
 0.997
icd
Isocitrate dehydrogenase.
 
 0.995
fumC
Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.978
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.953
prpD
2-methylcitrate dehydratase.
  
 
 0.936
prpB_2
2-methylisocitrate lyase.
   
 
 0.928
fadB
3-hydroxyacyl CoA dehydrogenase oxidoreductase protein; Belongs to the enoyl-CoA hydratase/isomerase family.
   
 0.923
yfcX
Enoyl CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.
   
 0.923
prpB_1
2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
  
 0.919
Your Current Organism:
Legionella birminghamensis
NCBI taxonomy Id: 28083
Other names: ATCC 43702, CCUG 31233, CCUG 31233 A, CIP 103871, DSM 19232, JCM 7559, L. birminghamensis, NCTC 12437
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