Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mdtAMultidrug efflux system, subunit A; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (393 aa)    
Predicted Functional Partners:
lmxF_2
Multidrug efflux pump.
  0.979
oprM
Outer membrane efflux protein.
 
 0.937
lmxF_3
Multidrug efflux pump.
 
  0.893
mexF2
Putative multidrug-efflux system transmembrane protein.
 
  0.892
lmxF_1
RND multidrug efflux transporter MexF.
 
  0.886
tolC_1
Outer membrane protein TolC.
  
 0.744
bepE_2
Multidrug efflux transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
  0.690
mdtC
Integral membrane protein, AcrB/AcrD/AcrF family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
  0.686
bepE_3
Multidrug efflux transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
  0.680
macB_1
ABC transporter permease.
  
   0.581
Your Current Organism:
Legionella birminghamensis
NCBI taxonomy Id: 28083
Other names: ATCC 43702, CCUG 31233, CCUG 31233 A, CIP 103871, DSM 19232, JCM 7559, L. birminghamensis, NCTC 12437
Server load: low (28%) [HD]