Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
lly4-hydroxyphenylpyruvate dioxygenase. (350 aa)    
Predicted Functional Partners:
hmgA
Homogentisate 1,2-dioxygenase.
 
 0.998
Lche_0222
Glutathione S-transferase (maleylacetoacetate isomerase).
 
  
 0.974
phhA
Phenylalanine-4-hydroxylase.
 
  
 0.964
Lche_0221
Fumarylacetoacetate hydrolase.
 
  
 0.962
hisC-2
Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
    
 0.925
hisC
Histidinol-phosphate aminotransferase (Imidazole acetol-phosphate transaminase); Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
    
 0.913
aspB
Aspartate aminotransferase.
   
 
 0.908
Lche_2994
Aspartate aminotransferase.
   
 
 0.908
Lche_1986
Pterin-4-alpha-carbinolamine dehydratase.
  
  
 0.845
GatA_1
Amidase.
  
 
  0.813
Your Current Organism:
Legionella cherrii
NCBI taxonomy Id: 28084
Other names: ATCC 35252, CCUG 29666, CIP 103842, DSM 19213, L. cherrii, Legionella cherryi, NCTC 11976, strain ORW
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