STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PlaOuter membrane protease. (308 aa)    
Predicted Functional Partners:
parC
DNA topoisomerase IV, A subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
   
    0.753
Lche_0544
Calcium-transporting ATPase.
  
     0.737
Lche_3036
Endoglucanase; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
  
     0.718
Lche_2120
Major facilitator family transporter.
  
     0.717
Lche_0316
Hypothetical protein.
  
     0.716
Lche_0252
L-gulono-gamma-lactone oxidase.
  
     0.709
minE
Septum formation topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
   
    0.707
Lche_2796
O-Antigen ligase.
  
     0.695
Lche_2502
2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase.
  
     0.689
Lche_2667
Hypothetical protein.
  
     0.669
Your Current Organism:
Legionella cherrii
NCBI taxonomy Id: 28084
Other names: ATCC 35252, CCUG 29666, CIP 103842, DSM 19213, L. cherrii, Legionella cherryi, NCTC 11976, strain ORW
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.