lvgA protein (Legionella cherrii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

lvgA

Virulence protein LvgA. (220 aa)

Predicted Functional Partners:

icmW

0.958

Lche_0622

0.955

Lche_0626

0.797

Lche_1729

0.768

feoA

0.706

feoB

0.706

Lche_0440

0.706

dotD

0.636

dotC

0.633

Lche_0436

0.435

Your Current Organism:

Legionella cherrii

NCBI taxonomy Id: 28084
Other names: ATCC 35252, CCUG 29666, CIP 103842, DSM 19213, L. cherrii, Legionella cherryi, NCTC 11976, strain ORW

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lche_0436	Lche_0440	Lche_0436	Lche_0440	Alpha/beta superfamily transporter hydrolase.	FeoC like transcriptional regulator.	0.707
Lche_0436	feoA	Lche_0436	Lche_0438	Alpha/beta superfamily transporter hydrolase.	Ferrous iron transporter A.	0.707
Lche_0436	feoB	Lche_0436	Lche_0439	Alpha/beta superfamily transporter hydrolase.	Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.	0.707
Lche_0436	lvgA	Lche_0436	Lche_0441	Alpha/beta superfamily transporter hydrolase.	Virulence protein LvgA.	0.435
Lche_0440	Lche_0436	Lche_0440	Lche_0436	FeoC like transcriptional regulator.	Alpha/beta superfamily transporter hydrolase.	0.707
Lche_0440	feoA	Lche_0440	Lche_0438	FeoC like transcriptional regulator.	Ferrous iron transporter A.	0.845
Lche_0440	feoB	Lche_0440	Lche_0439	FeoC like transcriptional regulator.	Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.	0.889
Lche_0440	lvgA	Lche_0440	Lche_0441	FeoC like transcriptional regulator.	Virulence protein LvgA.	0.706
Lche_0622	Lche_0626	Lche_0622	Lche_0626	Protein IcmS.	Protein IcmO (DotL).	0.963
Lche_0622	Lche_1729	Lche_0622	Lche_1729	Protein IcmS.	Phospholipase, patatin family.	0.556
Lche_0622	icmW	Lche_0622	Lche_0414	Protein IcmS.	Intracellular multiplication protein IcmW.	0.958
Lche_0622	lvgA	Lche_0622	Lche_0441	Protein IcmS.	Virulence protein LvgA.	0.955
Lche_0626	Lche_0622	Lche_0626	Lche_0622	Protein IcmO (DotL).	Protein IcmS.	0.963
Lche_0626	Lche_1729	Lche_0626	Lche_1729	Protein IcmO (DotL).	Phospholipase, patatin family.	0.556
Lche_0626	dotC	Lche_0626	Lche_0420	Protein IcmO (DotL).	Defect in organelle trafficking lipoprotein DotC.	0.868
Lche_0626	icmW	Lche_0626	Lche_0414	Protein IcmO (DotL).	Intracellular multiplication protein IcmW.	0.912
Lche_0626	lvgA	Lche_0626	Lche_0441	Protein IcmO (DotL).	Virulence protein LvgA.	0.797
Lche_1729	Lche_0622	Lche_1729	Lche_0622	Phospholipase, patatin family.	Protein IcmS.	0.556
Lche_1729	Lche_0626	Lche_1729	Lche_0626	Phospholipase, patatin family.	Protein IcmO (DotL).	0.556
Lche_1729	icmW	Lche_1729	Lche_0414	Phospholipase, patatin family.	Intracellular multiplication protein IcmW.	0.556