STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lche_0464Fatty acid desaturase. (393 aa)    
Predicted Functional Partners:
mutM
formamidopyrimidine-DNA glycosylase MutM; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
       0.724
Lche_0463
Hypothetical protein.
       0.724
plsC
1-acyl-sn-glycerol-3-phosphate acetyltransferase.
 
 
 
 0.692
fabG_2
3-oxoacyl-ACP reductase.
   
   0.647
PhaR
PHB/PHA accumulation regulator DNA-binding domain protein.
       0.594
Lche_0410
Zinc-finger domain protein.
  
     0.542
fabG_1
3-oxoacyl-ACP reductase.
   
   0.521
pksJ_1
Polyketide synthase, type I.
   
 0.457
Lche_1834
acyl-CoA synthetase.
   
 0.457
Lche_2715
acyl-CoA synthetase.
   
 0.457
Your Current Organism:
Legionella cherrii
NCBI taxonomy Id: 28084
Other names: ATCC 35252, CCUG 29666, CIP 103842, DSM 19213, L. cherrii, Legionella cherryi, NCTC 11976, strain ORW
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