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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cph2_2Inner membrane protein/sensory box protein LssE. (566 aa)    
Predicted Functional Partners:
Cph2_7
Regulatory protein (GGDEF, PAS, PAC domains).
 
 0.960
Cph2_4
Regulatory protein (GGDEF and EAL domains).
 
 
0.927
Cph2_5
Regulatory protein (GGDEF and EAL domains).
 
 
0.926
Gmr_3
Regulatory protein (GGDEF domain).
 
 
0.918
ArcB_1
Sensory box histidine kinase/response regulator.
 
 0.913
PleD_3
Sensory box/GGDEF family protein.
 
 0.911
LuxQ_2
Sensory histidine-kinase / response regulator.
 
 
 0.907
Lche_0508
Hypothetical protein.
      0.883
Cph2_3
Sensory box (GGDEF/EAL domain) regulatory protein.
 
 
 0.881
pleD
Sensor histidine kinase.
 
 
 0.837
Your Current Organism:
Legionella cherrii
NCBI taxonomy Id: 28084
Other names: ATCC 35252, CCUG 29666, CIP 103842, DSM 19213, L. cherrii, Legionella cherryi, NCTC 11976, strain ORW
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