close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lche_0592Carboxymuconolactone decarboxylase family transporter; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. (113 aa)    
Predicted Functional Partners:
Hgd
3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.
  
  
 0.626
Lche_0899
Hypothetical protein; Belongs to the UPF0276 family.
   
  
 0.613
lvhB3
Type IV secretion system protein VirB3.
   
    0.506
pksJ_1
Polyketide synthase, type I.
  
  
 0.490
Lche_1834
acyl-CoA synthetase.
  
  
 0.490
Lche_2715
acyl-CoA synthetase.
  
  
 0.490
Lche_1675
Signal peptide protein.
   
    0.480
msrA_1
Bifunctional methionine sulfoxide reductase B/A protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
     
 0.439
Lche_2186
Oxidoreductase, FAD-binding protein.
     
 0.408
Lche_2506
acyl-CoA synthetase.
   
  
 0.408
Your Current Organism:
Legionella cherrii
NCBI taxonomy Id: 28084
Other names: ATCC 35252, CCUG 29666, CIP 103842, DSM 19213, L. cherrii, Legionella cherryi, NCTC 11976, strain ORW
Server load: low (40%) [HD]