Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lche_0633IcmC (DotE). (193 aa)    
Predicted Functional Partners:
icmD_1
IcmD (DotP).
     
 0.890
dotF
Component of the Dot/Icm secretion system.
     
 0.866
Lche_0629
Protein IcmL (DotI).
     
 0.858
Lche_0630
IcmK protein.
     
 0.848
Lche_0631
Protein IcmE (DotG).
     
 0.841
icmM
IcmM (DotJ).
     
 0.830
lphA
LphA (DotK).
       0.791
Lche_0635
IcmJ protein.
     
 0.688
Lche_0636
Protein IcmB (DotO).
       0.660
Lche_0625
IcmP protein.
     
 0.559
Your Current Organism:
Legionella cherrii
NCBI taxonomy Id: 28084
Other names: ATCC 35252, CCUG 29666, CIP 103842, DSM 19213, L. cherrii, Legionella cherryi, NCTC 11976, strain ORW
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