Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CpxA_1Sensor histidine kinase. (417 aa)    
Predicted Functional Partners:
ompR_2
DNA-binding response regulator in two-component regulatory system with EnvZ.
 
 
 0.977
ArcB_1
Sensory box histidine kinase/response regulator.
 
 
0.880
LuxQ_2
Sensory histidine-kinase / response regulator.
 
 
0.875
cpxR
Transcriptional regulatory protein CpxR.
 
 
 0.848
lrpR
DNA-binding response regulator.
 
 
 0.826
ompR_1
DNA-binding response regulator in two-component regulatory system with EnvZ.
 
 
 0.823
EvgS
Sensory box histidine kinase/response regulator.
 
 
0.819
PdhB_1
Pyruvate/2-oxoglutarate dehydrogenase subunit E1.
   
 0.818
OmpR_2
Response regulator.
 
   0.806
fixL
Sensor histidine kinase.
 
 
 
 0.772
Your Current Organism:
Legionella cherrii
NCBI taxonomy Id: 28084
Other names: ATCC 35252, CCUG 29666, CIP 103842, DSM 19213, L. cherrii, Legionella cherryi, NCTC 11976, strain ORW
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