glnK protein (Legionella cherrii) - STRING interaction network

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glnK

Carbamoylphosphate synthase large subunit; Belongs to the P(II) protein family. (113 aa)

Predicted Functional Partners:

glnD

0.945

YqiC

0.755

yifB

0.654

glnA

0.622

PuuA

0.497

CheW_1

0.463

glnE

0.432

Your Current Organism:

Legionella cherrii

NCBI taxonomy Id: 28084
Other names: ATCC 35252, CCUG 29666, CIP 103842, DSM 19213, L. cherrii, Legionella cherryi, NCTC 11976, strain ORW

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CheW_1	glnK	Lche_3047	Lche_0679	Chemotaxis signal transduction protein (cheW domain).	Carbamoylphosphate synthase large subunit; Belongs to the P(II) protein family.	0.463
PuuA	glnA	Lche_1251	Lche_1793	Glutamine synthase; Belongs to the glutamine synthetase family.	Glutamine synthetase.	0.919
PuuA	glnK	Lche_1251	Lche_0679	Glutamine synthase; Belongs to the glutamine synthetase family.	Carbamoylphosphate synthase large subunit; Belongs to the P(II) protein family.	0.497
YqiC	glnK	Lche_0678	Lche_0679	Membrane fusogenic activity.	Carbamoylphosphate synthase large subunit; Belongs to the P(II) protein family.	0.755
YqiC	yifB	Lche_0678	Lche_0677	Membrane fusogenic activity.	Bifunctional enzyme and transcriptional regulator.	0.701
glnA	PuuA	Lche_1793	Lche_1251	Glutamine synthetase.	Glutamine synthase; Belongs to the glutamine synthetase family.	0.919
glnA	glnD	Lche_1793	Lche_1423	Glutamine synthetase.	PII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.	0.566
glnA	glnE	Lche_1793	Lche_0205	Glutamine synthetase.	Glutamine synthetase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transducti [...]	0.637
glnA	glnK	Lche_1793	Lche_0679	Glutamine synthetase.	Carbamoylphosphate synthase large subunit; Belongs to the P(II) protein family.	0.622
glnD	glnA	Lche_1423	Lche_1793	PII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.	Glutamine synthetase.	0.566
glnD	glnE	Lche_1423	Lche_0205	PII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.	Glutamine synthetase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transducti [...]	0.816
glnD	glnK	Lche_1423	Lche_0679	PII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.	Carbamoylphosphate synthase large subunit; Belongs to the P(II) protein family.	0.945
glnE	glnA	Lche_0205	Lche_1793	Glutamine synthetase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transducti [...]	Glutamine synthetase.	0.637
glnE	glnD	Lche_0205	Lche_1423	Glutamine synthetase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transducti [...]	PII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.	0.816
glnE	glnK	Lche_0205	Lche_0679	Glutamine synthetase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transducti [...]	Carbamoylphosphate synthase large subunit; Belongs to the P(II) protein family.	0.432
glnK	CheW_1	Lche_0679	Lche_3047	Carbamoylphosphate synthase large subunit; Belongs to the P(II) protein family.	Chemotaxis signal transduction protein (cheW domain).	0.463
glnK	PuuA	Lche_0679	Lche_1251	Carbamoylphosphate synthase large subunit; Belongs to the P(II) protein family.	Glutamine synthase; Belongs to the glutamine synthetase family.	0.497
glnK	YqiC	Lche_0679	Lche_0678	Carbamoylphosphate synthase large subunit; Belongs to the P(II) protein family.	Membrane fusogenic activity.	0.755
glnK	glnA	Lche_0679	Lche_1793	Carbamoylphosphate synthase large subunit; Belongs to the P(II) protein family.	Glutamine synthetase.	0.622
glnK	glnD	Lche_0679	Lche_1423	Carbamoylphosphate synthase large subunit; Belongs to the P(II) protein family.	PII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.	0.945