STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lche_08083',5'-cyclic-nucleotide phosphodiesterase. (327 aa)    
Predicted Functional Partners:
CyaA_1
Adenylate/guanylate cyclase transmembrane protein.
 
  
  0.931
CyaB_1
Guanylate/adenylate cyclase.
 
  
  0.925
ladC
Adenylate cyclase.
 
  
  0.915
cyaA
Fused adenylate cyclase/two component hybrid sensor/regulator.
    
  0.904
CyaB_2
Guanylate cyclase.
    
  0.902
Cya
Guanylate cyclase.
    
  0.902
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
     
  0.900
ppt_1
Hypoxanthine-guanine phosphoribosyltransferase.
     
  0.900
surE
Acid phosphatase SurE (Stationary phase survival protein); Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
  0.900
guaA
GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
  0.900
Your Current Organism:
Legionella cherrii
NCBI taxonomy Id: 28084
Other names: ATCC 35252, CCUG 29666, CIP 103842, DSM 19213, L. cherrii, Legionella cherryi, NCTC 11976, strain ORW
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