Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tolCOuter membrane protein TolC. (457 aa)    
Predicted Functional Partners:
acrA
RND efflux membrane fusion protein, acriflavin resistance protein E; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.944
MdtE
Hemolysin D; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 0.937
BepF
Membrane-fusion protein involved in transport; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 0.937
BepE_2
Multidrug efflux transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
 0.924
helA_2
HelA protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
 0.924
lmxF
Multidrug efflux pump.
  
 0.924
BepE_1
Multidrug efflux transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
 0.924
CusA
Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
 0.924
MdtP
Outer membrane efflux lipoprotein.
     
 0.906
TtgC_1
Outer membrane efflux protein.
     
 0.906
Your Current Organism:
Legionella cherrii
NCBI taxonomy Id: 28084
Other names: ATCC 35252, CCUG 29666, CIP 103842, DSM 19213, L. cherrii, Legionella cherryi, NCTC 11976, strain ORW
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