YicC protein (Legionella cherrii) - STRING interaction network

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Score

YicC

Putative stress-induced protein. (288 aa)

Predicted Functional Partners:

gmk

0.936

rpoZ

0.835

spoT

0.682

tdcF

0.682

rph

0.528

uup_2

0.404

Your Current Organism:

Legionella cherrii

NCBI taxonomy Id: 28084
Other names: ATCC 35252, CCUG 29666, CIP 103842, DSM 19213, L. cherrii, Legionella cherryi, NCTC 11976, strain ORW

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
YicC	gmk	Lche_1062	Lche_1063	Putative stress-induced protein.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.936
YicC	rph	Lche_1062	Lche_1060	Putative stress-induced protein.	Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.	0.528
YicC	rpoZ	Lche_1062	Lche_1064	Putative stress-induced protein.	RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.835
YicC	spoT	Lche_1062	Lche_1065	Putative stress-induced protein.	Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	0.682
YicC	tdcF	Lche_1062	Lche_1066	Putative stress-induced protein.	L-PSP (mRNA) endoribonuclease.	0.682
YicC	uup_2	Lche_1062	Lche_1067	Putative stress-induced protein.	ABC transporter ATP-binding protein.	0.404
gmk	YicC	Lche_1063	Lche_1062	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Putative stress-induced protein.	0.936
gmk	rph	Lche_1063	Lche_1060	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.	0.561
gmk	rpoZ	Lche_1063	Lche_1064	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.955
gmk	spoT	Lche_1063	Lche_1065	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	0.972
gmk	tdcF	Lche_1063	Lche_1066	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	L-PSP (mRNA) endoribonuclease.	0.715
gmk	uup_2	Lche_1063	Lche_1067	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	ABC transporter ATP-binding protein.	0.444
rph	YicC	Lche_1060	Lche_1062	Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.	Putative stress-induced protein.	0.528
rph	gmk	Lche_1060	Lche_1063	Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.561
rph	rpoZ	Lche_1060	Lche_1064	Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.	RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.608
rph	spoT	Lche_1060	Lche_1065	Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.	Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	0.559
rph	tdcF	Lche_1060	Lche_1066	Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.	L-PSP (mRNA) endoribonuclease.	0.663
rpoZ	YicC	Lche_1064	Lche_1062	RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	Putative stress-induced protein.	0.835
rpoZ	gmk	Lche_1064	Lche_1063	RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.955
rpoZ	rph	Lche_1064	Lche_1060	RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.	0.608