trxB protein (Legionella cherrii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

trxB

Thioredoxin reductase. (320 aa)

Predicted Functional Partners:

trxA_2

0.977

sufS

0.906

trxA_1

0.861

trx

0.855

ahpC_1

0.852

ahpC_2

0.852

Lche_2186

0.843

msrA_1

0.813

lolA

0.798

ftsK

0.762

Your Current Organism:

Legionella cherrii

NCBI taxonomy Id: 28084
Other names: ATCC 35252, CCUG 29666, CIP 103842, DSM 19213, L. cherrii, Legionella cherryi, NCTC 11976, strain ORW

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lche_2186	msrA_1	Lche_2186	Lche_2831	Oxidoreductase, FAD-binding protein.	Bifunctional methionine sulfoxide reductase B/A protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.	0.633
Lche_2186	trxB	Lche_2186	Lche_1364	Oxidoreductase, FAD-binding protein.	Thioredoxin reductase.	0.843
ahpC_1	msrA_1	Lche_0643	Lche_2831	Alkyl hydroperoxide reductase.	Bifunctional methionine sulfoxide reductase B/A protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.	0.644
ahpC_1	trxA_2	Lche_0643	Lche_2849	Alkyl hydroperoxide reductase.	Thioredoxin; Belongs to the thioredoxin family.	0.444
ahpC_1	trxB	Lche_0643	Lche_1364	Alkyl hydroperoxide reductase.	Thioredoxin reductase.	0.852
ahpC_2	msrA_1	Lche_2871	Lche_2831	Alkyl hydroperoxide reductase.	Bifunctional methionine sulfoxide reductase B/A protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.	0.644
ahpC_2	trxA_2	Lche_2871	Lche_2849	Alkyl hydroperoxide reductase.	Thioredoxin; Belongs to the thioredoxin family.	0.444
ahpC_2	trxB	Lche_2871	Lche_1364	Alkyl hydroperoxide reductase.	Thioredoxin reductase.	0.852
ftsK	lolA	Lche_1365	Lche_1366	DNA translocase FtsK.	Outer-membrane lipoprotein carrier protein precursor; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).	0.883
ftsK	trxB	Lche_1365	Lche_1364	DNA translocase FtsK.	Thioredoxin reductase.	0.762
lolA	ftsK	Lche_1366	Lche_1365	Outer-membrane lipoprotein carrier protein precursor; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).	DNA translocase FtsK.	0.883
lolA	trxB	Lche_1366	Lche_1364	Outer-membrane lipoprotein carrier protein precursor; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).	Thioredoxin reductase.	0.798
msrA_1	Lche_2186	Lche_2831	Lche_2186	Bifunctional methionine sulfoxide reductase B/A protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.	Oxidoreductase, FAD-binding protein.	0.633
msrA_1	ahpC_1	Lche_2831	Lche_0643	Bifunctional methionine sulfoxide reductase B/A protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.	Alkyl hydroperoxide reductase.	0.644
msrA_1	ahpC_2	Lche_2831	Lche_2871	Bifunctional methionine sulfoxide reductase B/A protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.	Alkyl hydroperoxide reductase.	0.644
msrA_1	trxB	Lche_2831	Lche_1364	Bifunctional methionine sulfoxide reductase B/A protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.	Thioredoxin reductase.	0.813
sufS	trxB	Lche_0491	Lche_1364	Selenocysteine lyase, PLP-dependent; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.	Thioredoxin reductase.	0.906
trx	trxB	Lche_1742	Lche_1364	Thioredoxin; Belongs to the thioredoxin family.	Thioredoxin reductase.	0.855
trxA_1	trxB	Lche_0293	Lche_1364	Thioredoxin.	Thioredoxin reductase.	0.861
trxA_2	ahpC_1	Lche_2849	Lche_0643	Thioredoxin; Belongs to the thioredoxin family.	Alkyl hydroperoxide reductase.	0.444