STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fleSSensor histidine kinase. (333 aa)    
Predicted Functional Partners:
fleR
Two-component response regulator.
 0.994
LuxQ_2
Sensory histidine-kinase / response regulator.
 
 
 0.916
ArcB_1
Sensory box histidine kinase/response regulator.
 
 
 0.916
EvgS
Sensory box histidine kinase/response regulator.
 
 
 0.905
letS
Legionella transmission sensor LetS.
 
 
 0.855
PdhB_1
Pyruvate/2-oxoglutarate dehydrogenase subunit E1.
  
 0.824
fliE
Flagellar hook-basal body complex protein.
 
 
 0.801
ompR_2
DNA-binding response regulator in two-component regulatory system with EnvZ.
 
 
 0.723
fliG
Flagellar motor switch protein; FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
  
  
 0.718
cpxR
Transcriptional regulatory protein CpxR.
 
 
 0.697
Your Current Organism:
Legionella cherrii
NCBI taxonomy Id: 28084
Other names: ATCC 35252, CCUG 29666, CIP 103842, DSM 19213, L. cherrii, Legionella cherryi, NCTC 11976, strain ORW
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.