minD protein (Legionella cherrii) - STRING interaction network

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Score

minD

Septum site-determining protein (cell division inhibitor). (276 aa)

Predicted Functional Partners:

minE

0.998

minC

0.998

mreC

0.721

mreD

0.711

guaA

0.667

guaB

0.655

tadA_1

0.612

MreB

0.531

rlmB

0.436

Your Current Organism:

Legionella cherrii

NCBI taxonomy Id: 28084
Other names: ATCC 35252, CCUG 29666, CIP 103842, DSM 19213, L. cherrii, Legionella cherryi, NCTC 11976, strain ORW

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MreB	minC	Lche_2068	Lche_1496	Rod shape determining protein MreB.	Cell division inhibitor MinC (septum placement); Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.	0.635
MreB	minD	Lche_2068	Lche_1418	Rod shape determining protein MreB.	Septum site-determining protein (cell division inhibitor).	0.531
MreB	mreC	Lche_2068	Lche_2067	Rod shape determining protein MreB.	Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.	0.998
MreB	mreD	Lche_2068	Lche_2066	Rod shape determining protein MreB.	Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family.	0.951
guaA	guaB	Lche_1420	Lche_1419	GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.999
guaA	minD	Lche_1420	Lche_1418	GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	Septum site-determining protein (cell division inhibitor).	0.667
guaA	minE	Lche_1420	Lche_1417	GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	Septum formation topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.	0.650
guaA	tadA_1	Lche_1420	Lche_1421	GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.	0.794
guaB	guaA	Lche_1419	Lche_1420	IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	0.999
guaB	minD	Lche_1419	Lche_1418	IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	Septum site-determining protein (cell division inhibitor).	0.655
guaB	minE	Lche_1419	Lche_1417	IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	Septum formation topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.	0.674
guaB	tadA_1	Lche_1419	Lche_1421	IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.	0.737
minC	MreB	Lche_1496	Lche_2068	Cell division inhibitor MinC (septum placement); Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.	Rod shape determining protein MreB.	0.635
minC	minD	Lche_1496	Lche_1418	Cell division inhibitor MinC (septum placement); Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.	Septum site-determining protein (cell division inhibitor).	0.998
minC	minE	Lche_1496	Lche_1417	Cell division inhibitor MinC (septum placement); Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.	Septum formation topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.	0.845
minC	mreC	Lche_1496	Lche_2067	Cell division inhibitor MinC (septum placement); Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.	Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.	0.893
minC	mreD	Lche_1496	Lche_2066	Cell division inhibitor MinC (septum placement); Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.	Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family.	0.900
minD	MreB	Lche_1418	Lche_2068	Septum site-determining protein (cell division inhibitor).	Rod shape determining protein MreB.	0.531
minD	guaA	Lche_1418	Lche_1420	Septum site-determining protein (cell division inhibitor).	GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	0.667
minD	guaB	Lche_1418	Lche_1419	Septum site-determining protein (cell division inhibitor).	IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.655