STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
odpBPyruvate dehydrogenase E1 subunit beta. (324 aa)    
Predicted Functional Partners:
odp
Branched-chain alpha-keto acid dehydrogenase subunit E2.
 
 0.999
odpA
Pyruvate dehydrogenase E1 alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
 0.999
aceF
Pyruvate dehydrogenase (dihydrolipoyltransacetylase component) E2p.
 
 0.997
lpdA
Dihydrolipoyl dehydrogenase.
 
 0.990
sucB
Dihydrolipoamide succinyltransferase subunit E2; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 0.988
PdhB_1
Pyruvate/2-oxoglutarate dehydrogenase subunit E1.
 
0.969
Lche_2004
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
  
 
 0.937
Lche_1311
Putative CoA-dependent acyltransferase.
  
 0.930
MerA
Oxydoreductase.
 
 0.921
pykA
Pyruvate kinase II; Belongs to the pyruvate kinase family.
  
 
 0.917
Your Current Organism:
Legionella cherrii
NCBI taxonomy Id: 28084
Other names: ATCC 35252, CCUG 29666, CIP 103842, DSM 19213, L. cherrii, Legionella cherryi, NCTC 11976, strain ORW
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.