node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AldA | Pta | Lche_1357 | Lche_1544 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Phosphate acetyl/butaryl transferase. | 0.857 |
AldA | acsB | Lche_1357 | Lche_3069 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.928 |
AldA | mmsA | Lche_1357 | Lche_3071 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Methylmalonate-semialdehyde dehydrogenase [acylating] (MMSDH), oxidoreductase. | 0.913 |
AldA | prpC | Lche_1357 | Lche_1523 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 2-methylcitrate synthase; Belongs to the citrate synthase family. | 0.856 |
AldA | yfcX | Lche_1357 | Lche_1464 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Enoyl CoA hydratase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.927 |
AldA | ywdH | Lche_1357 | Lche_2380 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.914 |
Pta | AldA | Lche_1544 | Lche_1357 | Phosphate acetyl/butaryl transferase. | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.857 |
Pta | acsB | Lche_1544 | Lche_3069 | Phosphate acetyl/butaryl transferase. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.957 |
Pta | mmsA | Lche_1544 | Lche_3071 | Phosphate acetyl/butaryl transferase. | Methylmalonate-semialdehyde dehydrogenase [acylating] (MMSDH), oxidoreductase. | 0.928 |
Pta | prpB | Lche_1544 | Lche_1522 | Phosphate acetyl/butaryl transferase. | 2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. | 0.871 |
Pta | prpC | Lche_1544 | Lche_1523 | Phosphate acetyl/butaryl transferase. | 2-methylcitrate synthase; Belongs to the citrate synthase family. | 0.978 |
Pta | succ | Lche_1544 | Lche_0449 | Phosphate acetyl/butaryl transferase. | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.871 |
Pta | yfcX | Lche_1544 | Lche_1464 | Phosphate acetyl/butaryl transferase. | Enoyl CoA hydratase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.931 |
Pta | ywdH | Lche_1544 | Lche_2380 | Phosphate acetyl/butaryl transferase. | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.857 |
acnA | prpB | Lche_1649 | Lche_1522 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. | 0.686 |
acnA | prpC | Lche_1649 | Lche_1523 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 2-methylcitrate synthase; Belongs to the citrate synthase family. | 0.857 |
acnA | prpD | Lche_1649 | Lche_1524 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 2-methylcitrate dehydratase. | 0.632 |
acnA | yfcX | Lche_1649 | Lche_1464 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Enoyl CoA hydratase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.593 |
acsB | AldA | Lche_3069 | Lche_1357 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.928 |
acsB | Pta | Lche_3069 | Lche_1544 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Phosphate acetyl/butaryl transferase. | 0.957 |