Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
ackAAcetate kinase (Acetokinase); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (390 aa)    
Predicted Functional Partners:
Pta
Phosphate acetyl/butaryl transferase.
 
 0.999
pta
Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase.
  
 0.958
acsB
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
     
 0.923
yccX
Acylphosphatase.
     
 0.912
ywdH
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
    
 0.903
MaeB_1
NADP-dependent malic enzyme.
  
  
 0.832
xfp
Xylulose-5-phosphate/fructose-6-phosphate phosphoketolase.
  
 0.824
Lche_1546
Hypothetical protein.
       0.800
Lche_2004
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
     
 0.638
Lche_2183
Hypothetical protein.
  
 0.526
Your Current Organism:
Legionella cherrii
NCBI taxonomy Id: 28084
Other names: ATCC 35252, CCUG 29666, CIP 103842, DSM 19213, L. cherrii, Legionella cherryi, NCTC 11976, strain ORW
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