trx protein (Legionella cherrii) - STRING interaction network

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[Homology]

Score

trx

Thioredoxin; Belongs to the thioredoxin family. (121 aa)

Predicted Functional Partners:

adk

0.877

trxB

0.855

rir1

0.845

htpB

0.778

Lche_1744

0.719

Lche_2706

0.616

Lche_1745

0.539

CopA_1

0.469

grpE

0.464

gor

0.462

Your Current Organism:

Legionella cherrii

NCBI taxonomy Id: 28084
Other names: ATCC 35252, CCUG 29666, CIP 103842, DSM 19213, L. cherrii, Legionella cherryi, NCTC 11976, strain ORW

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CopA_1	trx	Lche_2719	Lche_1742	Cation transport ATPase.	Thioredoxin; Belongs to the thioredoxin family.	0.469
Lche_1744	Lche_1745	Lche_1744	Lche_1745	Transcriptional regulator.	3'-5' exonuclease.	0.664
Lche_1744	adk	Lche_1744	Lche_1743	Transcriptional regulator.	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	0.719
Lche_1744	trx	Lche_1744	Lche_1742	Transcriptional regulator.	Thioredoxin; Belongs to the thioredoxin family.	0.719
Lche_1745	Lche_1744	Lche_1745	Lche_1744	3'-5' exonuclease.	Transcriptional regulator.	0.664
Lche_1745	adk	Lche_1745	Lche_1743	3'-5' exonuclease.	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	0.540
Lche_1745	trx	Lche_1745	Lche_1742	3'-5' exonuclease.	Thioredoxin; Belongs to the thioredoxin family.	0.539
Lche_2706	trx	Lche_2706	Lche_1742	Hypothetical protein.	Thioredoxin; Belongs to the thioredoxin family.	0.616
adk	Lche_1744	Lche_1743	Lche_1744	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	Transcriptional regulator.	0.719
adk	Lche_1745	Lche_1743	Lche_1745	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	3'-5' exonuclease.	0.540
adk	grpE	Lche_1743	Lche_2402	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	Heat-shock protein GrpE(HSP-70 cofactor); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Sever [...]	0.549
adk	rir1	Lche_1743	Lche_1805	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.938
adk	trx	Lche_1743	Lche_1742	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	Thioredoxin; Belongs to the thioredoxin family.	0.877
gor	htpB	Lche_2527	Lche_0201	Glutathione reductase.	Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.428
gor	trx	Lche_2527	Lche_1742	Glutathione reductase.	Thioredoxin; Belongs to the thioredoxin family.	0.462
gor	trxB	Lche_2527	Lche_1364	Glutathione reductase.	Thioredoxin reductase.	0.547
grpE	adk	Lche_2402	Lche_1743	Heat-shock protein GrpE(HSP-70 cofactor); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Sever [...]	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	0.549
grpE	htpB	Lche_2402	Lche_0201	Heat-shock protein GrpE(HSP-70 cofactor); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Sever [...]	Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.993
grpE	rir1	Lche_2402	Lche_1805	Heat-shock protein GrpE(HSP-70 cofactor); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Sever [...]	Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.682
grpE	trx	Lche_2402	Lche_1742	Heat-shock protein GrpE(HSP-70 cofactor); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Sever [...]	Thioredoxin; Belongs to the thioredoxin family.	0.464