| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Dus | fis_2 | Lche_2797 | Lche_1787 | tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Global DNA-binding transcriptional dual regulator; Belongs to the transcriptional regulatory Fis family. | 0.797 |
| Dus | rpsR | Lche_2797 | Lche_1469 | tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. | 0.564 |
| Gmr_3 | fis_2 | Lche_1926 | Lche_1787 | Regulatory protein (GGDEF domain). | Global DNA-binding transcriptional dual regulator; Belongs to the transcriptional regulatory Fis family. | 0.557 |
| IolG_2 | enhA_3 | Lche_1785 | Lche_1788 | Oxidoreductase. | Enhanced entry protein EnhA. | 0.434 |
| IolG_2 | fis_2 | Lche_1785 | Lche_1787 | Oxidoreductase. | Global DNA-binding transcriptional dual regulator; Belongs to the transcriptional regulatory Fis family. | 0.581 |
| IolG_2 | lpxB_1 | Lche_1785 | Lche_1786 | Oxidoreductase. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.834 |
| IolG_2 | rnhB | Lche_1785 | Lche_1784 | Oxidoreductase. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.558 |
| enhA_3 | IolG_2 | Lche_1788 | Lche_1785 | Enhanced entry protein EnhA. | Oxidoreductase. | 0.434 |
| enhA_3 | fis_2 | Lche_1788 | Lche_1787 | Enhanced entry protein EnhA. | Global DNA-binding transcriptional dual regulator; Belongs to the transcriptional regulatory Fis family. | 0.610 |
| enhA_3 | lpxB_1 | Lche_1788 | Lche_1786 | Enhanced entry protein EnhA. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.477 |
| fis_2 | Dus | Lche_1787 | Lche_2797 | Global DNA-binding transcriptional dual regulator; Belongs to the transcriptional regulatory Fis family. | tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 0.797 |
| fis_2 | Gmr_3 | Lche_1787 | Lche_1926 | Global DNA-binding transcriptional dual regulator; Belongs to the transcriptional regulatory Fis family. | Regulatory protein (GGDEF domain). | 0.557 |
| fis_2 | IolG_2 | Lche_1787 | Lche_1785 | Global DNA-binding transcriptional dual regulator; Belongs to the transcriptional regulatory Fis family. | Oxidoreductase. | 0.581 |
| fis_2 | enhA_3 | Lche_1787 | Lche_1788 | Global DNA-binding transcriptional dual regulator; Belongs to the transcriptional regulatory Fis family. | Enhanced entry protein EnhA. | 0.610 |
| fis_2 | lpxB_1 | Lche_1787 | Lche_1786 | Global DNA-binding transcriptional dual regulator; Belongs to the transcriptional regulatory Fis family. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.631 |
| fis_2 | rnhB | Lche_1787 | Lche_1784 | Global DNA-binding transcriptional dual regulator; Belongs to the transcriptional regulatory Fis family. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.485 |
| fis_2 | rpsR | Lche_1787 | Lche_1469 | Global DNA-binding transcriptional dual regulator; Belongs to the transcriptional regulatory Fis family. | 30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. | 0.507 |
| fis_2 | yjbN | Lche_1787 | Lche_1690 | Global DNA-binding transcriptional dual regulator; Belongs to the transcriptional regulatory Fis family. | tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 0.646 |
| lpxB_1 | IolG_2 | Lche_1786 | Lche_1785 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Oxidoreductase. | 0.834 |
| lpxB_1 | enhA_3 | Lche_1786 | Lche_1788 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Enhanced entry protein EnhA. | 0.477 |