mdlB protein (Legionella cherrii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

mdlB

Multidrug ABC transporter ATPase/permease. (214 aa)

Predicted Functional Partners:

dnaK

0.757

pksJ_1

0.645

Lche_1834

0.645

Lche_2715

0.645

LagD

0.635

thrS

0.602

uup_3

0.563

ksgA

0.547

ccmA

0.545

uup_1

0.503

Your Current Organism:

Legionella cherrii

NCBI taxonomy Id: 28084
Other names: ATCC 35252, CCUG 29666, CIP 103842, DSM 19213, L. cherrii, Legionella cherryi, NCTC 11976, strain ORW

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LagD	mdlB	Lche_3138	Lche_1810	Toxin secretion ABC transporter ATP-binding protein.	Multidrug ABC transporter ATPase/permease.	0.635
Lche_1834	Lche_2715	Lche_1834	Lche_2715	acyl-CoA synthetase.	acyl-CoA synthetase.	0.999
Lche_1834	dnaK	Lche_1834	Lche_2401	acyl-CoA synthetase.	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.932
Lche_1834	ksgA	Lche_1834	Lche_2839	acyl-CoA synthetase.	Dimethyladenosine transferase (16S rRNA dimethylase); Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.	0.451
Lche_1834	mdlB	Lche_1834	Lche_1810	acyl-CoA synthetase.	Multidrug ABC transporter ATPase/permease.	0.645
Lche_1834	pksJ_1	Lche_1834	Lche_0504	acyl-CoA synthetase.	Polyketide synthase, type I.	0.999
Lche_1834	thrS	Lche_1834	Lche_0391	acyl-CoA synthetase.	threonyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.	0.524
Lche_2715	Lche_1834	Lche_2715	Lche_1834	acyl-CoA synthetase.	acyl-CoA synthetase.	0.999
Lche_2715	dnaK	Lche_2715	Lche_2401	acyl-CoA synthetase.	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.932
Lche_2715	ksgA	Lche_2715	Lche_2839	acyl-CoA synthetase.	Dimethyladenosine transferase (16S rRNA dimethylase); Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.	0.451
Lche_2715	mdlB	Lche_2715	Lche_1810	acyl-CoA synthetase.	Multidrug ABC transporter ATPase/permease.	0.645
Lche_2715	pksJ_1	Lche_2715	Lche_0504	acyl-CoA synthetase.	Polyketide synthase, type I.	0.999
Lche_2715	thrS	Lche_2715	Lche_0391	acyl-CoA synthetase.	threonyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.	0.524
ccmA	ksgA	Lche_2028	Lche_2839	Heme exporter protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.	Dimethyladenosine transferase (16S rRNA dimethylase); Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.	0.547
ccmA	mdlB	Lche_2028	Lche_1810	Heme exporter protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.	Multidrug ABC transporter ATPase/permease.	0.545
dnaK	Lche_1834	Lche_2401	Lche_1834	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	acyl-CoA synthetase.	0.932
dnaK	Lche_2715	Lche_2401	Lche_2715	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	acyl-CoA synthetase.	0.932
dnaK	ksgA	Lche_2401	Lche_2839	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	Dimethyladenosine transferase (16S rRNA dimethylase); Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.	0.594
dnaK	mdlB	Lche_2401	Lche_1810	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	Multidrug ABC transporter ATPase/permease.	0.757
dnaK	pksJ_1	Lche_2401	Lche_0504	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	Polyketide synthase, type I.	0.932