STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pilZ_2Type IV pilus assembly PilZ. (185 aa)    
Predicted Functional Partners:
FliS
Flagellar protein FliS.
 
  
 0.861
fliD
Flagellar hook associated protein 2 FliD; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
 
  
 0.860
flgK
Flagellar hook-associated protein FlgK; Belongs to the flagella basal body rod proteins family.
 
  
 0.786
Lche_1956
Coiled-coil protein.
       0.780
Lche_0672
Type II/III secretion system protein.
  
     0.767
SecA_2
Coiled-coil protein.
  
     0.750
Lche_1836
Hypothetical protein.
  
     0.743
yggX
Protein that protects iron-sulfur proteins against oxidative damage; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
       0.742
ankK
Substrate of the Dot/Icm secretion system.
  
     0.741
CheW_1
Chemotaxis signal transduction protein (cheW domain).
  
  
 0.731
Your Current Organism:
Legionella cherrii
NCBI taxonomy Id: 28084
Other names: ATCC 35252, CCUG 29666, CIP 103842, DSM 19213, L. cherrii, Legionella cherryi, NCTC 11976, strain ORW
Server load: low (22%) [HD]