sdhL protein (Legionella cherrii) - STRING interaction network

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Score

sdhL

L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (458 aa)

Predicted Functional Partners:

glyA

0.966

Lche_0869

0.920

trpA

0.913

pssA

0.900

trpB

0.900

GloA

0.800

mip

0.678

AmpG_1

0.627

gcvT

0.565

Lche_2484

0.496

Your Current Organism:

Legionella cherrii

NCBI taxonomy Id: 28084
Other names: ATCC 35252, CCUG 29666, CIP 103842, DSM 19213, L. cherrii, Legionella cherryi, NCTC 11976, strain ORW

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AmpG_1	mip	Lche_2084	Lche_2085	AmpG protein.	Macrophage infectivity potentiator.	0.733
AmpG_1	sdhL	Lche_2084	Lche_2086	AmpG protein.	L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.	0.627
GloA	sdhL	Lche_2937	Lche_2086	Lactoylglutathione lyase.	L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.	0.800
GloA	trpA	Lche_2937	Lche_1319	Lactoylglutathione lyase.	Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.	0.800
GloA	trpB	Lche_2937	Lche_1318	Lactoylglutathione lyase.	Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.	0.816
Lche_0869	glyA	Lche_0869	Lche_0973	Phosphoserine phosphatase.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.935
Lche_0869	pssA	Lche_0869	Lche_0702	Phosphoserine phosphatase.	CDP-diacylglycerol-serine O-phosphatidyltransferase (phosphatidylserine synthase); Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.903
Lche_0869	sdhL	Lche_0869	Lche_2086	Phosphoserine phosphatase.	L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.	0.920
Lche_0869	trpA	Lche_0869	Lche_1319	Phosphoserine phosphatase.	Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.	0.904
Lche_0869	trpB	Lche_0869	Lche_1318	Phosphoserine phosphatase.	Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.	0.921
Lche_2484	sdhL	Lche_2484	Lche_2086	DNA uptake/competence protein ComA.	L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.	0.496
gcvT	glyA	Lche_3052	Lche_0973	Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.998
gcvT	sdhL	Lche_3052	Lche_2086	Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine.	L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.	0.565
glyA	Lche_0869	Lche_0973	Lche_0869	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Phosphoserine phosphatase.	0.935
glyA	gcvT	Lche_0973	Lche_3052	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine.	0.998
glyA	pssA	Lche_0973	Lche_0702	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	CDP-diacylglycerol-serine O-phosphatidyltransferase (phosphatidylserine synthase); Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.900
glyA	sdhL	Lche_0973	Lche_2086	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.	0.966
glyA	trpA	Lche_0973	Lche_1319	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.	0.928
glyA	trpB	Lche_0973	Lche_1318	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.	0.922
mip	AmpG_1	Lche_2085	Lche_2084	Macrophage infectivity potentiator.	AmpG protein.	0.733