STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lche_2105Diphosphomevalonate decarboxylase. (315 aa)    
Predicted Functional Partners:
Lche_2104
Mevalonate kinase.
 
  
 0.986
fni
Isopentenyl pyrophosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
 
  
 0.968
ispA
Geranyltranstransferase; Belongs to the FPP/GGPP synthase family.
  
 0.934
mvaA
Hydroxymethylglutaryl CoA reductase; Belongs to the HMG-CoA reductase family.
 
  
 0.865
Lche_2114
Hypothetical protein.
  
  
 0.736
cpoB
Outer membrane protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.
       0.735
pal
Peptidoglycan-associated lipoprotein precursor (19 kDa surface antigen) (PPL); Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
       0.735
Lche_0121
alanyl-tRNA synthetase.
    
   0.725
AlaS_1
alanyl-tRNA synthetase.
    
   0.725
Lche_2108
Transport protein.
       0.638
Your Current Organism:
Legionella cherrii
NCBI taxonomy Id: 28084
Other names: ATCC 35252, CCUG 29666, CIP 103842, DSM 19213, L. cherrii, Legionella cherryi, NCTC 11976, strain ORW
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