STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lche_2125ATP-binding transmembrane ABC transporter. (597 aa)    
Predicted Functional Partners:
Lche_2124
ABC transporter ATP binding transmembrane protein.
 
    
0.817
abcT
ABC transporter ATP-binding protein.
  
 
0.663
Lche_0070
Multidrug resistance ABC transporter ATP binding protein.
  
 
0.658
msbA
Lipid A export ATP-binding/permease MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
  
 
0.651
mrp
ATPase; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
    
 0.605
mdlB
Multidrug ABC transporter ATPase/permease.
  
 
0.602
Lche_2123
Hypothetical protein.
       0.554
Lche_2126
D-xylose reductase III.
       0.526
Lche_2127
GNAT family acetyltransferase.
  
    0.518
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
   
 0.491
Your Current Organism:
Legionella cherrii
NCBI taxonomy Id: 28084
Other names: ATCC 35252, CCUG 29666, CIP 103842, DSM 19213, L. cherrii, Legionella cherryi, NCTC 11976, strain ORW
Server load: medium (46%) [HD]
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