close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ptaBifunctional enoyl-CoA hydratase/phosphate acetyltransferase. (468 aa)    
Predicted Functional Partners:
ack
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
  
 0.990
ackA
Acetate kinase (Acetokinase); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
  
 0.963
phbC_2
Polyhydroxyalkanoic synthase.
  
 0.923
fabI_2
enoyl-ACP reductase.
 
  
 0.900
Ldh
Leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
 
  
 0.857
PdhB_1
Pyruvate/2-oxoglutarate dehydrogenase subunit E1.
  
  
 0.815
prpC
2-methylcitrate synthase; Belongs to the citrate synthase family.
  
 
 0.790
gltA
Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.790
katA
Catalase.
   
 0.782
Lche_2163
Putative S-isoprenylcysteine methyltransferase.
       0.715
Your Current Organism:
Legionella cherrii
NCBI taxonomy Id: 28084
Other names: ATCC 35252, CCUG 29666, CIP 103842, DSM 19213, L. cherrii, Legionella cherryi, NCTC 11976, strain ORW
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.