Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lche_2260Putative virulence protein. (470 aa)    
Predicted Functional Partners:
ankK
Substrate of the Dot/Icm secretion system.
  
     0.751
Lche_2153
Protein LvrA.
  
     0.751
Lche_0958
IcmL-like protein.
 
     0.745
dotA
Defect in organelle trafficking protein DotA.
  
     0.741
Lche_1692
Hypothetical protein.
  
     0.728
Lche_2524
Sphingomyelin phosphodiesterase.
  
     0.728
Lche_1903
General secretion pathway protein L; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.
  
     0.720
Lche_2306
Hypothetical protein.
  
     0.719
Lche_2838
Putative helicase/relaxase.
  
     0.719
SecA_2
Coiled-coil protein.
  
     0.718
Your Current Organism:
Legionella cherrii
NCBI taxonomy Id: 28084
Other names: ATCC 35252, CCUG 29666, CIP 103842, DSM 19213, L. cherrii, Legionella cherryi, NCTC 11976, strain ORW
Server load: low (10%) [HD]