Lche_2516 protein (Legionella cherrii) - STRING interaction network

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Score

Lche_2516

GTP cyclohydrolase II. (422 aa)

Predicted Functional Partners:

Lche_2517

0.994

ribH

0.900

ribD

0.897

ribE

0.882

upp

0.860

birA

0.576

Lche_2515

0.537

sdaC

0.475

Lche_2186

0.457

AcpP

0.454

Your Current Organism:

Legionella cherrii

NCBI taxonomy Id: 28084
Other names: ATCC 35252, CCUG 29666, CIP 103842, DSM 19213, L. cherrii, Legionella cherryi, NCTC 11976, strain ORW

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AcpP	Lche_2186	Lche_2513	Lche_2186	Acyl carrier protein.	Oxidoreductase, FAD-binding protein.	0.445
AcpP	Lche_2515	Lche_2513	Lche_2515	Acyl carrier protein.	Transmembrane protein.	0.670
AcpP	Lche_2516	Lche_2513	Lche_2516	Acyl carrier protein.	GTP cyclohydrolase II.	0.454
AcpP	Lche_2517	Lche_2513	Lche_2517	Acyl carrier protein.	Putative biotin synthetase like protein.	0.454
Lche_2186	AcpP	Lche_2186	Lche_2513	Oxidoreductase, FAD-binding protein.	Acyl carrier protein.	0.445
Lche_2186	Lche_2516	Lche_2186	Lche_2516	Oxidoreductase, FAD-binding protein.	GTP cyclohydrolase II.	0.457
Lche_2515	AcpP	Lche_2515	Lche_2513	Transmembrane protein.	Acyl carrier protein.	0.670
Lche_2515	Lche_2516	Lche_2515	Lche_2516	Transmembrane protein.	GTP cyclohydrolase II.	0.537
Lche_2515	Lche_2517	Lche_2515	Lche_2517	Transmembrane protein.	Putative biotin synthetase like protein.	0.537
Lche_2515	upp	Lche_2515	Lche_2518	Transmembrane protein.	Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.	0.452
Lche_2516	AcpP	Lche_2516	Lche_2513	GTP cyclohydrolase II.	Acyl carrier protein.	0.454
Lche_2516	Lche_2186	Lche_2516	Lche_2186	GTP cyclohydrolase II.	Oxidoreductase, FAD-binding protein.	0.457
Lche_2516	Lche_2515	Lche_2516	Lche_2515	GTP cyclohydrolase II.	Transmembrane protein.	0.537
Lche_2516	Lche_2517	Lche_2516	Lche_2517	GTP cyclohydrolase II.	Putative biotin synthetase like protein.	0.994
Lche_2516	birA	Lche_2516	Lche_2092	GTP cyclohydrolase II.	biotin-[acetylCoA carboxylase] holoenzyme synthetase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.	0.576
Lche_2516	ribD	Lche_2516	Lche_1189	GTP cyclohydrolase II.	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.	0.897
Lche_2516	ribE	Lche_2516	Lche_2758	GTP cyclohydrolase II.	Riboflavin synthase alpha chain.	0.882
Lche_2516	ribH	Lche_2516	Lche_2733	GTP cyclohydrolase II.	Riboflavin synthase beta chain (6,7-dimethyl-8-ribityllumazine synthase); Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family.	0.900
Lche_2516	sdaC	Lche_2516	Lche_2519	GTP cyclohydrolase II.	Serine transporter.	0.475
Lche_2516	upp	Lche_2516	Lche_2518	GTP cyclohydrolase II.	Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.	0.860