ligD protein (Legionella cherrii) - STRING interaction network

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Score

ligD

DNA ligase D. (835 aa)

Predicted Functional Partners:

ykoV

0.969

polA

0.961

dnaN

0.937

hisB

0.680

DnaX

0.672

Lche_0213

0.629

YecE

0.592

Lche_1636

0.574

xthA

0.495

exoA

0.495

Your Current Organism:

Legionella cherrii

NCBI taxonomy Id: 28084
Other names: ATCC 35252, CCUG 29666, CIP 103842, DSM 19213, L. cherrii, Legionella cherryi, NCTC 11976, strain ORW

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DnaX	Lche_0213	Lche_1760	Lche_0213	DNA polymerase III, delta' subunit.	Type III restriction enzyme, res subunit.	0.563
DnaX	Lche_1636	Lche_1760	Lche_1636	DNA polymerase III, delta' subunit.	Mechanosensitive ion channel MscS.	0.570
DnaX	dnaN	Lche_1760	Lche_2908	DNA polymerase III, delta' subunit.	DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...]	0.996
DnaX	ligD	Lche_1760	Lche_2925	DNA polymerase III, delta' subunit.	DNA ligase D.	0.672
DnaX	polA	Lche_1760	Lche_3025	DNA polymerase III, delta' subunit.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.930
Lche_0213	DnaX	Lche_0213	Lche_1760	Type III restriction enzyme, res subunit.	DNA polymerase III, delta' subunit.	0.563
Lche_0213	Lche_1636	Lche_0213	Lche_1636	Type III restriction enzyme, res subunit.	Mechanosensitive ion channel MscS.	0.726
Lche_0213	dnaN	Lche_0213	Lche_2908	Type III restriction enzyme, res subunit.	DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...]	0.690
Lche_0213	ligD	Lche_0213	Lche_2925	Type III restriction enzyme, res subunit.	DNA ligase D.	0.629
Lche_0213	polA	Lche_0213	Lche_3025	Type III restriction enzyme, res subunit.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.980
Lche_1636	DnaX	Lche_1636	Lche_1760	Mechanosensitive ion channel MscS.	DNA polymerase III, delta' subunit.	0.570
Lche_1636	Lche_0213	Lche_1636	Lche_0213	Mechanosensitive ion channel MscS.	Type III restriction enzyme, res subunit.	0.726
Lche_1636	ligD	Lche_1636	Lche_2925	Mechanosensitive ion channel MscS.	DNA ligase D.	0.574
Lche_1636	polA	Lche_1636	Lche_3025	Mechanosensitive ion channel MscS.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.964
YecE	ligD	Lche_2376	Lche_2925	Hypothetical protein.	DNA ligase D.	0.592
YecE	ykoV	Lche_2376	Lche_2926	Hypothetical protein.	Putative DNA repair protein YkoV; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.	0.444
dnaN	DnaX	Lche_2908	Lche_1760	DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...]	DNA polymerase III, delta' subunit.	0.996
dnaN	Lche_0213	Lche_2908	Lche_0213	DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...]	Type III restriction enzyme, res subunit.	0.690
dnaN	exoA	Lche_2908	Lche_2467	DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...]	Exodeoxyribonuclease.	0.847
dnaN	ligD	Lche_2908	Lche_2925	DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...]	DNA ligase D.	0.937