Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Lche_3020Two-component response regulator. (157 aa)    
Predicted Functional Partners:
CheA
Chemotaxis histidine kinase.
  
 
 0.981
CheW_1
Chemotaxis signal transduction protein (cheW domain).
  
 
 0.928
Lche_0814
CheW-like domain protein.
  
 
 0.908
CheR
Methyltransferase involved in chemotaxis (CheR domain).
  
  
 0.833
FliM
Flagellar protein; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
  
  
 0.805
FlhF
Flagellar GTP-binding protein FlhF.
  
  
 0.798
LuxQ_2
Sensory histidine-kinase / response regulator.
  
 
 0.779
ArcB_1
Sensory box histidine kinase/response regulator.
  
 
 0.779
Gmr_3
Regulatory protein (GGDEF domain).
  
  
 0.774
fliN
Flagellar motor switch protein FliN; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.
  
  
 0.739
Your Current Organism:
Legionella cherrii
NCBI taxonomy Id: 28084
Other names: ATCC 35252, CCUG 29666, CIP 103842, DSM 19213, L. cherrii, Legionella cherryi, NCTC 11976, strain ORW
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