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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mmsAMethylmalonate-semialdehyde dehydrogenase [acylating] (MMSDH), oxidoreductase. (499 aa)    
Predicted Functional Partners:
Hgd
3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.
 
 
 0.968
acsB
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
  
 0.967
prpC
2-methylcitrate synthase; Belongs to the citrate synthase family.
  
 0.928
Pta
Phosphate acetyl/butaryl transferase.
  
 
 0.928
GabT
4-aminobutyrate aminotransferase.
  
 0.928
yfcX
Enoyl CoA hydratase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.927
DgdA
Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 0.924
ArgD_2
Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.924
ywdH
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
  
 
0.921
AldA
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
  
 
0.913
Your Current Organism:
Legionella cherrii
NCBI taxonomy Id: 28084
Other names: ATCC 35252, CCUG 29666, CIP 103842, DSM 19213, L. cherrii, Legionella cherryi, NCTC 11976, strain ORW
Server load: medium (46%) [HD]
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