Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lvhB_7Vir protein. (100 aa)    
Predicted Functional Partners:
lvhB_5
Vir protein B5.
       0.838
lvhB3
Type IV secretion system protein VirB3.
       0.838
lvrC
Pleiotropic regulatory protein for carbon source metabolism; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small [...]
       0.816
lvhB_6
Vir protein.
       0.809
Lche_3107
Hypothetical protein.
       0.788
Lche_3108
Hypothetical protein.
       0.763
Lche_3099
Hypothetical protein.
       0.711
Lche_3096
Hypothetical protein; Part of the Type IV secretion system. Belongs to the GSP E family.
       0.682
Lche_3095
Hypothetical protein.
       0.681
lvrD
Legionella vir region protein.
       0.566
Your Current Organism:
Legionella cherrii
NCBI taxonomy Id: 28084
Other names: ATCC 35252, CCUG 29666, CIP 103842, DSM 19213, L. cherrii, Legionella cherryi, NCTC 11976, strain ORW
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