Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
salLAdenosyl-chloride synthase. (320 aa)    
Predicted Functional Partners:
oatA_4
Acetyltransferase.
       0.840
guaA
GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
    
  0.594
Lcin_2677
Inosine 5'-monophosphate dehydrogenase.
     
  0.549
xapA
Xanthosine phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
     
  0.549
Lcin_0019
Hypothetical protein.
       0.500
guaC
Guanosine monophosphate reductase GuaC.
     
  0.485
add_1
Adenosine deaminase.
     
  0.485
add_2
Adenosine deaminase.
     
  0.485
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
  0.485
nudC
NADH pyrophosphatase.
     
  0.483
Your Current Organism:
Legionella cincinnatiensis
NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H
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