Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
abcTABC transporter ATP-binding protein. (600 aa)    
Predicted Functional Partners:
rkpA
Type I polyketide synthase WcbR.
   
 0.802
tycC_2
Non-ribosomal peptide synthase.
  
 
 0.700
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.658
pksM
Polyketide synthase.
   
 0.652
metN
DL-methionine transporter subunit, ATP-binding component of ABC superfamily protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.
 
    
0.612
hlyB
ABC transporter.
 
 
 
0.594
SunT
Hypothetical protein; ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain.
   
  0.534
thrS
threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).
  
   0.528
uup_3
ABC transporter ATP-binding protein.
 
 
   0.508
lolD_2-2
ABC transporter ATP binding protein.
     0.507
Your Current Organism:
Legionella cincinnatiensis
NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H
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